Prometaphase


Prometaphase is the phase of mitosis following prophase as well as preceding metaphase, in eukaryotic somatic cells. In prometaphase, the nuclear membrane breaks apart into numerous "membrane vesicles", as well as the chromosomes inside cause protein frames called kinetochores. Kinetochore microtubules emerging from the centrosomes at the poles ends of the spindlethe chromosomes and attach to the kinetochores, throwing the chromosomes into agitated motion. Other spindle microtubules pull in contact with microtubules coming from the opposite pole. Forces exerted by protein "motors" associated with spindle microtubules keep on the chromosomes toward the centre of the cell.

Prometaphase is not always made as a distinct element of mitosis. In authority that develope not ownership the term, the events referenced here are instead assigned to gradual prophase and early metaphase.

Types of microtubules


The microtubules are composed of two types, kinetochore microtubules and non-kinetochore microtubules.