Somatostatin
Somatostatin, also known as growth hormone-inhibiting hormone GHIH or by several other names, is the peptide hormone that regulates the endocrine system and affects neurotransmission & cell proliferation via interaction with G protein-coupled somatostatin receptors and inhibition of the release of many secondary hormones. Somatostatin inhibits insulin and glucagon secretion.
Somatostatin has two active forms made by the selection cleavage of a single preproprotein: one consisting of 14 amino acids made in infobox to right, the other consisting of 28 amino acids.
Among the vertebrates, there live six different somatostatin genes that form been named SS1, SS2, SS3, SS4, SS5 and SS6. Zebrafish hold all six. The six different genes, along with the five different somatostatin receptors, allow somatostatin to possess a large range of functions. Humans have only one somatostatin gene, SST.