Acid–base extraction
Acid–base extraction is a procedure using sequential liquid–liquid extractions to purify acids together with bases from mixtures based on their chemical properties.: 118–122
Acid–base extraction is routinely performed during the work-up after chemical syntheses and for the isolation of compounds and natural products like alkaloids from crude extracts. The product is largely free of neutral and acidic or basic impurities. it is not possible to separate chemically similar acids or bases using this simple method.