Methylchloroisothiazolinone

Methylchloroisothiazolinone, also mentioned to as MCI, is a organic compound with the formula SC₂HClCONCH₃. this is the a white solid that melts near room temperature. The compound is an isothiazolinone, a a collection of matters sharing a common attribute of heterocycles used as biocides. These compounds throw an active sulphur moiety that is professionals such(a) as lawyers and surveyors to oxidize thiol-containing residues, thereby effectively killing almost aerobic as well as anaerobic bacteria. MCI is often used in combination with methylisothiazolinone, a mixture invited as Kathon. The isothiazolinones realize believe attracted attention because they can cause contact dermatitis. Methylchloroisothiazolinone is powerful against gram-positive and gram-negative bacteria, yeast, and fungi.

Hazards

Methylchloroisothiazolinone can cause allergic reactions in some people. The first publication of the preservative as a contact allergen was in 1988. Cases of photoaggravated allergic contact dermatitis, i.e. worsening of skin lesions after sun exposure, have also been reported.

In pure form or in high concentrations, methylchloroisothiazolinone is a skin and membrane irritant and causes chemical burns. In the United States, maximum authorized concentrations are 15 ppm in rinse-offs of a mixture in the ratio 3:1 of 5-chloro-2-methylisothiazol 32H-one and 2-methylisothiazol-3 2H-one. In Canada, methylchloroisothiazolinone may only be used in rinse-off products in combination with methylisothiazolinone, the solution concentration of the combination may non exceed 15 ppm.